Micky van de Ven Brace Halts The Toffees' Unbeaten Streak at New Home Ground
Micky van de Ven became the first defender to score two goals in a Premier League game for Spurs since the Belgian defender in March 2013.
At a glance
The Spurs defender nods into the net twice in first half
The home side's defender has goal disallowed after VAR review
Senegalese midfielder nets final goal in dying moments
The defeat is the Merseyside club's initial at their new ground
Micky van de Ven found the net on two occasions as Spurs extended their winning streak in away games in the top division and handed the Toffees their initial loss at Hill Dickinson Stadium.
Everton were undefeated in their five previous fixtures at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after 133 years at the end of the previous campaign.
But Spurs captain Van de Ven struck twice from corners in the opening 45 minutes to place their strong form at risk, and they were failed to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward the Brazilian - nodded in a final goal to put the game to bed.
Jake O'Brien believed he had levelled the scores a short while after the defender's first goal, directing a powerful header past Guglielmo Vicario from an Everton corner.
Beto, meanwhile, missed a handful of chances, while the Italian goalkeeper made a succession of fine stops to guarantee the London club went five away games unbeaten in the English top flight.
But the VAR intervened, instructing the match official to review the goal on the screen and the official decided that Jack Grealish and the attacker were in an illegal position and had interfered with the Spurs keeper.
The win moves Thomas Frank's team into third place in the division, five points off local foes and table-toppers the Gunners.
Everton stay in 14th position and are half a dozen points clear of the relegation zone.
Spurs breakdown: Van de Ven fulfils role at both ends of the field
Following a drab weekday display in the European competition against Monaco, where they mustered a only two shots on target, the manager chose the French striker up front instead of former Toffees player Richarlison.
The new arrival was unable to make much of an impact before being substituted for the substitute after an hour on the field, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman converted into an offensive threat to be reckoned with.
Spurs' opening strike came from a well-worked set-piece play, with Rodrigo Bentancur directing the ball toward the six-yard box for an unmarked the defender to head home.
And Ven de Ven - filling in as skipper in the Argentine's absence - notched his second in first-half stoppage time as he rose above Jordan Pickford to head home.
The Dutchman was equally impressive in defensive duties, combining well with Kevin Danso as the duo dealt superbly with the 34 crosses sent their way by Everton.
Everton analysis: Everton missing striker's instinct
Everton's recent stadium had been a happy hunting ground, but it appears the novelty may have worn off somewhat and fans flocked to the gates after the midfielder's final goal for Spurs.
The break in Everton's unbeaten home run won't be a massive concern for the manager, but their striker situation are.
Beto and Thierno Barry - the Toffees' pair of recognised centre-forwards - had netted only a single goal between them before the weekend's match.
And they were unable to contribute to that poor tally on a damp and dreary evening on in Liverpool.
The striker's form was summed up when he opted to overhead kick a golden opportunity from close range, despite having room and time to readjust for a more conventional attempt that would have challenged the keeper.
Barry, too, failed to make an impact after replacing Beto in the second half.
It was not for a lack of opportunity. Most of Everton's attacks came through the winger and the forward, who relentlessly delivered dangerous balls into the Spurs box.
Upcoming fixtures for both teams?
The Toffees: Moyes' men head to the Stadium of Light in the Premier League on early November at 20:00 GMT.
Spurs: Spurs travel to Newcastle's ground on Wednesday, 29 October for their next round League Cup match against the Magpies.